Familial sarcoidosis terminating as neurosarcoidosis.

Introduction Sarcoidosis is a systemic disease with numerous manifestations and modes of presentation. Amongst the rarer aspects are: (1) familial incidence, (2) transient generalized lymphadenopathy, (3) involvement of the mucous membrane of the upper respiratory tract, and (4) involvement of the central nervous system (CNS). Detailed necropsy findings in cases of neurosarcoidosis have been recorded comparatively infrequently. The following case is reported as a full necropsy was carried out and as a combination of all four of the above features was observed which, it is believed, has not been noted before.